Charleston vs Spartanburg: Physician Assistant Salary (2026)
Compare physician assistant salaries between Charleston, SC and Spartanburg, SC. All figures are 2026 estimates projected from BLS 2025 data.
Side-by-Side Comparison
| Metric | Charleston, SC | Spartanburg, SC |
|---|---|---|
| Median Salary | $133,200▲ | $126,040 |
| Hourly Rate | $64.04▲ | $60.60 |
| Entry Level (P10) | $80,373 | $103,031▲ |
| 25th Percentile | $113,611 | $115,388▲ |
| 75th Percentile | $138,862▲ | $136,713 |
| Top Earner (P90) | $163,514 | $171,842▲ |
| Total Employed | 620▲ | 80 |
Verdict
Charleston, SC offers better overall compensation for physician assistants, winning 3 out of 4 metrics compared to Spartanburg.
The salary gap between Charleston and Spartanburg is $7,160 (5.68%). Charleston's median is -5.12% compared to the US national median of $140,391.
Salary Range Comparison
The full salary range (10th to 90th percentile) in Charleston spans $83,141,Spartanburg spans $68,811. Charleston has a wider pay range, meaning more potential for high earners but also more variation.
Cost-of-Living Adjusted Comparison
After cost-of-living adjustment, Spartanburg ($138,428 effective) pays 4.92% more than Charleston ($131,931 effective).
Cost-of-living adjustment: salary × (100 / CoL index). Index of 100 = national average.
Which City Is Right for You?
Choose Charleston if…
- ✓Higher median salary ($133,200/year)
- ✓Larger job market (620 employed)
- ✓You prefer the South Carolina area and lifestyle
Choose Spartanburg if…
- ✓Better top-earner potential ($171,842)
- ✓Better purchasing power (CoL-adjusted: $138,428)
- ✓You prefer the South Carolina area and lifestyle
Historical Salary Growth Comparison
Based on BLS OEWS metropolitan area data, physician assistant salaries in Charleston grew 33.0% from 2019 to 2025, compared to 11.0% growth in Spartanburg over the same period.
Charleston, SC
$96,910 (2019) → $128,920 (2025)
Spartanburg, SC
$109,940 (2019) → $121,990 (2025)
View Full Salary Data
Charleston, SC
Spartanburg, SC
Frequently Asked Questions
Which city pays physician assistants more: Charleston or Spartanburg?
What is the hourly rate difference between Charleston and Spartanburg?
Should I relocate from Charleston to Spartanburg as a physician assistant?
What do entry-level physician assistants earn in Charleston vs Spartanburg?
Written by Jessica Tran, MPAS, PA-C
Career Analyst
Jessica has 10 years of experience as a physician assistant. Her specialty is cardiology in an outpatient setting.
Methodology & Data Source
All salary figures are 2026 projections based on BLS OEWS May 2025 data. A 3.32% CAGR (derived from 6-year national BLS trends) was applied to estimate current compensation. Cost-of-living adjustments use BEA Regional Price Parity data. Actual salaries vary by employer, certifications, and experience.
Data Sources & Methodology
Source: BLS, OEWS , released .
Compiled and verified by Jessica Tran, MPAS, PA-C, a licensed physician assistant with 10+ years of clinical experience. · View source data at BLS.gov