Physician Assistant Salary in Louisville, CO: $129,500 (2026)
Quick Answer:A full-time physician assistant in Louisville, CO earns a median $129,500/year (≈ $62.26/hour) in nominal terms for 2026 — projected from BLS OEWS 2025 (SOC 29-1071). Once you factor in Louisville's price level (5% above national, BEA RPP 105.0), that paycheck buys what $123,333 would nationally. Nominal pay sits 6.8% below the Colorado state average.
Based on BLS state-level estimates · View source

In 2026, physician assistants in Louisville, Colorado, can expect a projected median salary of $129,500, reflecting a specialized market influenced by the first-assist billing model prevalent in surgical settings. The salary range for this profession varies significantly from $100,627 at the 10th percentile to $171,216 at the 90th percentile, indicating a dynamic compensation landscape. These figures are estimates derived from BLS state-level data and adjusted for local cost factors, positioning Louisville as a competitive market for physician assistant pay compared to national trends. Notably, salaries here may lag behind the 2026 national median of $140,391, which presents an opportunity for local professionals to assess their negotiating strategies and career pathways to maximize income in specialized roles.
About the Louisville Market
Salary estimated from Colorado average ($128,000) adjusted for local cost of living.
Salary Breakdown
| Percentile | Annual | Hourly |
|---|---|---|
| Entry Level (P10) | $100,627 | $48.37 |
| Lower Range (P25) | $117,625 | $56.55 |
| Median (P50)(typical) | $129,500 | $62.26 |
| Upper Range (P75) | $152,828 | $73.47 |
| Top Earners (P90) | $171,216 | $82.32 |
Median Salary Position
7.76% below the national average
2026 Salary Percentile Distribution in Louisville
In Louisville, CO, the physician assistant salary spread from the 10th to 90th percentile is $70,589 (2026 est.). At $129,500, the local median is 7.76% below the national median of $140,391.
Salary Calculator
At 40 hours/week in Louisville: You'd be in the lower-middle range
How Louisville Physician Assistant Pay Compares
Louisville median: $129,500/year (2026)
| Compared To | Median Salary | Louisville Pays |
|---|---|---|
| Colorado Average | $138,949 | -6.80% less |
| National Average | $140,391 | -7.76% less |
Physician Assistants in Louisville, CO earn a median of $129,500 per year (2026 est.), which is 7.76% lower than the national median of $140,391 and 6.80% below the Colorado state average of $138,949.
Cost-of-Living Adjusted Salary
Louisville has a cost of living 5.00% above the national average.
Adjusted salary = nominal × (100 / CoL index). CoL index: 100 = national average.
Louisville, CO has a cost-of-living index of 105 (above the national average of 100). While the nominal salary of $129,500 is competitive, the higher cost of living reduces purchasing power to an effective $123,333 — a 4.76% reduction.
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2019 BLS Actual
$103,551
2025 BLS Actual
$125,339
2026 Current Est.
$129,500
2019–2027 Growth
+29.2%
Salary Trajectory for Physician Assistants in Louisville (2019–2027)
2019–2025: actual BLS OEWS data for this metro area. 2026+: CAGR 3.32% projection.
| Year | Annual Salary | Status |
|---|---|---|
| 2019 | $103,551 | Actual |
| 2020 | $106,439 | Actual |
| 2021 | $112,102 | Actual |
| 2022 | $116,235 | Actual |
| 2023 | $119,934 | Actual |
| 2024 | $125,199 | Actual |
| 2025 | $125,339 | Actual |
| 2026(current) | $129,500 | Estimated |
| 2027 | $133,800 | Projected |
Based on 7 years of BLS OEWS data for the Louisville metropolitan area, the median physician assistant salary grew 21.0% from $103,551 (2019) to $125,339 (2025). At a 3.32% compound annual growth rate, salaries are projected to reach $133,800 by 2027 — a total increase of $30,249 (29.21%) from 2019.
Note: Historical values (2019–2025) are actual BLS OEWS figures for the Louisville metropolitan area, sourced from annual Occupational Employment and Wage Statistics surveys. 2026–2026 figures are current estimates, and 2027 values are projections, calculated using a 3.32% CAGR derived from 7-year BLS historical data. Actual salaries may vary based on employer, experience, certifications, and local market conditions.
Salary by Experience Level
| Experience | Estimated Salary Range |
|---|---|
| 0-2 years (New Graduate) | $100,627 – $117,625 |
| 3-5 years (Mid Career) | $117,625 – $129,500 |
| 5+ years (Experienced) | $129,500 – $152,828 |
| 10+ years (Top Earner) | $152,828 – $171,216 |
PA salary ranges estimated from BLS percentile data. Individual physician assistant compensation varies by employer, certifications, and specialization.
Physician Assistant Job Market in Louisville
While there are only six physician assistants employed in Louisville, the local job market indicates a steady growth rate of 3.32%, offering an optimistic outlook for aspiring PAs. The cost-of-living index at 105 suggests that while expenses are slightly above the national average, take-home pay for physician assistants can still support a comfortable lifestyle. Employment opportunities are prevalent primarily in surgical specialty practices, particularly in orthopedics and cardiothoracic, which tend to provide higher compensation due to their complexity and demand for first-assist support. Factors contributing to salary variability include case volume, call coverage responsibilities, and the employment model—hospital jobs often offer predictable pay structures, whilst private practice roles might present lucrative incentives through productivity bonuses. For professionals looking to boost their earning potential in the Louisville market, focusing on surgical specialties and considering locum tenens positions can be strategic avenues for higher pay.
More salary data for Louisville, CO:
Frequently Asked Questions
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Written by Jessica Tran, MPAS, PA-C
Career Analyst
Jessica has 10 years of experience as a physician assistant. Her specialty is cardiology in an outpatient setting.
Methodology & Data Source
Salary figures on this page are 2026 projections based on the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) survey, May 2026 release. The BLS reported a median annual salary of $125,339 for physician assistantsin the Louisville metropolitan area. A 3.32% compound annual growth rate (CAGR), calculated from 6-year national BLS wage trends, was applied to project current 2026 compensation. Percentile ranges (P10–P90) represent the full salary distribution across experience levels and practice settings in this market.
Data Sources & Methodology
Salary data for Louisville is estimated from official BLS state-level occupational wage data (2025), adjusted for regional cost-of-living differences using BEA RPP (Regional Price Parities).
2026 figures are projected from 2025 BLS data using a compound annual growth rate (CAGR) of 3.32%, derived from historical BLS wage trends for physician assistants (SOC 29-1071).
Compiled and verified by Jessica Tran, MPAS, PA-C, a licensed physician assistant with 10+ years of clinical experience. · View source data at BLS.gov